The Action of Anabolic Steroids

Author: smithhall | Posted: 29.03.2012

A normal man produces 20 times more testosterone than a normal woman. This layer is responsible for the excess over the development of strong muscles in men, as well as the development of other sexual characteristics like facial hair and lower voice. Testosterone is working on this, when absorbed from the bloodstream by certain cells. The molecules themselves are of testosterone in the right places inside cells, called receptors, as well as a key part of the corresponding lock. When the receptor is occupied with the right type of molecule, it instructs the cell to perform specific functions. For example, in muscle cells supports the production of testosterone is protein. Within each cell there is a fixed number of receptors. If only several of them occupied the desired molecule, the cell responds weakly. When all the cell responds to the maximum level. A normal man allocates enough testosterone in the blood to fill the majority of receptors. However, if it takes large doses of anabolic steroids, as do the lifters, the cells will not do more than they would do on a lower dose because the receptors are already fully packed, and beyond the statutory number of molecules will not take testosterone. Excess testosterone will only make side effects more likely.

Did steroids cause the growth of the body and muscles? There is no evidence that extremely large doses of steroids by themselves will cause muscle growth, but due to chemical reactions. In many animals, high doses of anabolic steroids stimulate muscle growth is not higher than normal doses do. However, there is evidence that steroids enhance muscle growth when taking regular exercise and comply with high-protein diet. Anabolic steroids in his work balance between anabolic and catabolic processes in the body.

Anabolism - is a creative process in which simpler substances are transformed into more complex, bone and muscle tissue. Catabolism - is the appropriate destructive process that breaks down these complex tissues and removes them from the body. A functioning body tries to balance between these two processes, performing ongoing maintenance and replacement of tissues. Nitrogen balance is the difference between the total amount of nitrogen, the body use and quantity of nitrogen, an organism isolated. In the adult, no longer growing organism, this balance should be near zero or slightly above. Anabolic steroids reduce the catabolic effect of increasing the production of muscle protein. It is believed that steroids penetrate the cell and take the free androgen receptors. The newly formed steroid-receptor complex moves to the nucleus, contacts with RNA and causes a backup. The development of RNA increases, causing increased protein synthesis. Ultimately, all this leads to an increase in strength and muscle size. To an athlete accumulating muscle mass, his body must maintain a positive nitrogen balance, that is, the body must do more nitrogen than to stand out. During resistance training the body enters a selection of glucocorticosteroids in negative nitrogen balance. After class, the body is temporarily in a positive balance in which to add new muscle tissue protein structures.

Then, nitrogen balance goes to zero. Without the use of anabolic steroids, muscle mass builds up very slowly. Anabolic steroids are catabolic effect is neutralized, it leads to a positive nitrogen balance and a more rapid gain in muscle mass. However, maintaining a positive nitrogen balance did not last long, 1-2 months, even if you keep upping the dose of steroids. The body tries to maintain homeostasis and is highly addictive (tachyphylaxis) to steroids. An example of a homeostatic mechanism - the rise of cortisol in the blood at the use of steroids. This may counteract the effect of anabolic and catabolic support. To maintain a positive nitrogen balance, the athlete increases, and increases the dose of anabolic steroids, and this increases the risk of side effects. There is some evidence that anabolic steroids are forced to work as an athlete in training more and more intensively. This psychological effect may be more important than any direct chemical action. More frequent and more severe exercise may be the cause of frequent cases of damage to the connective tissue associated with steroid use.

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